Determination of Prostate Specific Antigen in chronic patients attending the San Lorenzo Hospital, San Lorenzo Municipality, Nicaragua

Abstract

The objective of the research was to determine the concentration of Prostate Specific Antigen (PSA) in chronic patients attending the Primary Hospital "Ahmed Campos Corea" El Papayal, San Lorenzo and to associate endogenous and exogenous factors that may cause alteration by means of the Chi-square statistic. The study had a quantitative approach and a descriptive, prospective and cross-sectional scope. The information was obtained by means of surveys applied to 30 patients, from whom blood samples (serum) were also extracted to measure PSA by ELISA method. The data obtained were processed in SPSS 21 and the graphs were extracted from Excel 2013. Ages ranged from 50 to 79 years with a mean of 63 ±10. Mestizo ethnicity was found in 100% and family history 16.7%. Alcoholism was present in 33.33%, smoking 20%, sedentary lifestyle 53.3%, fatty meat consumption 80%, BMI >30 36.7%, contact with herbicides and pesticides 60% and active sexual activity 73.3%. The chronic diseases they suffered from were hypertension 86.7% and type II diabetes 6.7%. The PSA concentration obtained varied from 0.1 to 12.1 ng/ml, with a mean of 1.52 ng/ml. PSA alteration was found in 10% of the patients under study, related in 18.18% with the risk factors associated with prostatic neoplasia. There was only variable dependence between endogenous factors age (X²: 20.74; VC 11.070) and family history (X²:6.0; VC: 3.841).