COVID-19 and MAIZ protocol as prophylactic treatment in Honduras, 2020: Literature Review.

Abstract

Honduras is in the position 68th worldwide with 4, 151 reported deaths and 170, 304 confirmed cases of COVID-19 as of March 1st, 2021. This literature review was conducted to provide a scientific perspective on the use of the MAIZ protocol (Microdacyn, Azithromycin, Ivermectin and Zinc) proposed for therapeutic and prophylactic uses during the early infection/viral response phase and asymptomatic contacts of COVID-19. A literature review was conducted from government institutions and international agencies guidelines, scientific articles, and studies in PubMed, The Lancet, SciELO. The review was limited to articles in Spanish and English published between 2010 and the 1st of March 2021, concluding that the MAIZ protocol lacks scientific evidence that supports the effectiveness against COVID-19, and clinical trials are needed to support its use responsibly.