Feocromocytoma: Diagnosis And Treatment

Abstract

Background. Pheochromocytoma is a low-prevalence tumor that originates in the chromaffin cells of the medulla of the adrenal glands. These tumors like normal sympathetic tissue originate from the neuroectoderm, being its main intraadrenal location. At the extra adrenal level they are also known as parangangliomas that are of 3 types 1, 3, 4, and are due to gene mutations coding for the subunits B, C, and D of succinate dehydrogenase, a mitochondrial enzyme involved in the Krebs, being frequent in Von Hippel Lindau’s disease, multiple endocrine neoplasia type 2Ay 2B and neurofibromatosis type 1. Objective: The written presentation focuses on showing the reader the accumulated evidence to the present time through a comprehensive review of Pheochromocytoma to clinically orient these Patients and thus reach an early diagnosis and treatment. METHODS: A search for original articles, systematic reviews, and review articles on PUBMED, SCIELO, and HINARI journal was conducted with years of coverage from 2010 to 2016. Development and Conclusion. Pheochromocytoma in a threatening disease due to its cardiovascular morbidity, these manifestations are associated with the hormones that catecholamines produce. Open or laparoscopic surgical treatment represents the definitive cure for this condition depending on the characteristics of the tumor and the patient, has satisfactory and comparable results to diagnose the tumor in time and avoid complications.