Toxicological Characterization of Chemical Products Used in Cleaning Activities in Nicaragua
DOI:
https://doi.org/10.5377/ul.v13i2.22829Keywords:
cleaning products, hazardous substances, chemical risk, chemical safety, Globally Harmonized SystemAbstract
A wide variety of chemical products with relevant toxicological properties are used in cleaning activities, yet their characterization in Nicaragua remains limited. This study aimed to characterize the main chemical products used in cleaning tasks in nine sites across the country, describing their use, functional and chemical classification, toxicological properties, and recommended safety measures for handling. A descriptive cross-sectional study was conducted in nine educational, administrative, and service institutions. Product characterization was performed through documentary review of technical datasheets, safety data sheets, and international regulations, complemented by direct on-site observation. Products were classified according to functional category, chemical family, and toxicological properties. Recommended safety measures for safe handling were also identified. The most frequently used products were sodium hypochlorite (100%), alkaline detergents (99.1%), formaldehyde-based air fresheners (99.1%), Ajax-type surfactants (46.2%), paraffinic waxes (30.2%), phenolic compounds (29.2%), and acetic acid (18.9%). Predominant chemical families included hypochlorites, strong alkalis, aldehydes, phenols, and anionic surfactants, all exhibiting irritant, corrosive, or sensitizing properties. Most products lacked labeling in accordance with the Globally Harmonized System. The findings highlight the presence of products with relevant toxicological hazards that require specific preventive measures, improved hazard communication, and promotion of safer handling practices.
Downloads
6
References
Archangelidi, O., Sathiyajit, S., Consonni, D., Jarvis, D., & De Matteis, S. (2020). Cleaning products and respiratory health outcomes in occupational cleaners: A systematic review and meta-analysis. Occupational and Environmental Medicine, 78(8), 604–617. https://doi.org/10.1136/oemed-2020-106774
Bello, A., Quinn, M. M., Perry, M. J., & Milton, D. K. (2009). Characterization of occupational exposures to cleaning products used for common cleaning tasks—a pilot study of hospital cleaners. Environmental Health, 8, 11. https://doi.org/10.1186/1476-069X-8-11
Cammalleri, V., Pocino, R., Marotta, D., Protano, C., Simonazzi, S., Petyx, M., . . . Vitali, M. (2021). Occupational scenarios and exposure assessment to formaldehyde: A systematic review. Indoor Air, 32(1). https://doi.org/10.1111/ina.12949
Carslaw, N., Fletcher, L., Heard, D. E., Ingham, T., & Walker, H. (2017). Significant production of OH from surface cleaning reactions. Indoor Air, 27(6), 1091–1100. https://doi.org/10.1111/ina.12394
Centers for Disease Control and Prevention, & National Institute for Occupational Safety and Health. (2019). NIOSH pocket guide to chemical hazards. U.S. Department of Health and Human Services. https://www.cdc.gov/niosh/npg/
Centers for Disease Control and Prevention, & National Institute for Occupational Safety and Health. (2021). Sodium hydroxide. NIOSH Workplace Safety and Health Topics. https://www.cdc.gov/niosh/topics/sodiumhydroxide/
Clausen, P., Frederiksen, M., Sejbæk, C., Sørli, J., Hougaard, K., Frydendall, K., . . . Wolkoff, P. (2020). Chemicals inhaled from spray cleaning and disinfection products and their respiratory effects: A comprehensive review. International Journal of Hygiene and Environmental Health, 229. https://doi.org/10.1016/j.ijheh.2020.113592
European Chemicals Agency. (2017). Guidance on the application of the CLP criteria: Guidance to Regulation (EC) No 1272/2008 on classification, labelling and packaging (CLP) of substances and mixtures (Version 5.0). European Chemicals Agency. https://echa.europa.eu/guidance-documents/guidance-on-clp
International Agency for Research on Cancer. (2012). Formaldehyde. In IARC monographs on the evaluation of carcinogenic risks to humans (Vol. 100F, pp. 401–435). World Health Organization, International Agency for Research on Cancer. https://monographs.iarc.who.int/wp-content/uploads/2018/06/mono100F-29.pdf
ILO. (2022). Seguridad química y medio ambiente. https://www.ilo.org/es/temas-y-sectores/seguridad-y-salud-en-el-trabajo/seguridad-quimica-y-medio-ambiente
Kathare, M., Julander, A., Erfani, B., & Schenk, L. (2022). An Overview of Cleaning Agents’ Health Hazards and Occupational Injuries and Diseases Attributed to Them in Sweden. Annals of Work Exposures and Health, 66(6), 741–753. https://doi.org/10.1093/annweh/wxac006
Nematollahi, N., Wang, H., Jayaratne, R., Thompson, M., Morawska, L., & Xian, H. (2019). Volatile chemical emissions from fragranced consumer products: A review. Building and Environment, 160, 106172. https://doi.org/10.1016/j.buildenv.2019.106172
Organization for Economic Co-operation and Development. (2015). Guidance on hazard communication for chemicals. OECD Publishing. https://www.oecd.org/chemicalsafety/risk-assessment/
OMS. (2016). Exposure to hazardous chemicals. En Occupational hazards in the health sector. https://www.who.int/tools/occupational-hazards-in-health-sector/exposure-to-hazardous-chemicals
Protano, C., Buomprisco, G., Cammalleri, V., Pocino, R., Marotta, D., & Simonazzi, S. (2021). The carcinogenic effects of formaldehyde occupational exposure: A systematic review. Cancers, 14(1), 165. https://doi.org/10.3390/cancers14010165.
Slaughter, R., Watts, M., Vale, J., Grieve, J., & Schep, L. (2019). The clinical toxicology of sodium hypochlorite. Clinical Toxicology, 57(5), 303–311. https://doi.org/10.1080/15563650.2018.1543889
Steinemann, A., Nematollahi, N., Weinberg, J. L., Flattery, J., Goodman, N., & Kolev, S. D. (2020). Volatile chemical emissions from common consumer products. Air Quality, Atmosphere & Health, 13, 1371–1380. https://doi.org/10.1007/s11869-020-00886-8
United Nations. (2019). Globally Harmonized System of Classification and Labelling of Chemicals (GHS) (8th rev. ed.). United Nations.
Vearrier, D., Jacobs, D., & Greenberg, M. (2015). Phenol toxicity following cutaneous exposure to creolin®: A case report. J Med Toxicol, 11(2), 227-231. https://doi.org/10.1007/s13181-014-0440-1.
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Universidad Nacional Autónoma de Nicaragua, León

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Copyright © 2026 Universitas (León), Revista Cientifíca de la UNAN-León. Academic Direction. Research Department. Publication and Scientific Event Unit.
