Polyostotic Fibrous Dysplasia

Abstract

Fibrous dysplasia (FD) or bone dysplasia is a rare bone development anomaly, with a frequency of between 5% and 7% of benign bone tumors, within these lesions, 50-70% are monostotic, 20-30% They are polyostotic and 3%-10% have McCune-Albright syndrome (DF, skin pigmentation and precocious puberty). It is characterized by the replacement of normal bone and bone marrow by fibrous tissue. A 15-year-old mixed-race male patient with a history of repeated fractures and bone deformity is presented. A diagnosis is established by imaging where lytic lesions are observed with a positive biopsy for FD. The condition has no specific treatment, its approach is multidisciplinary and represents a medical challenge.