Beta Blockers Intoxication

Authors

  • Enrique Adalberto Medina Pérez Third year resident of the Pediatrics Postgraduate Program at UNAH-VS
  • Melissa Portillo Intensivist Pediatrician of the Honduran Institute of Social Security
  • Linda Banegas Intensivist Pediatrician of the Honduran Institute of Social Security
  • Belinda Velásquez Intensivist Pediatrician of the Honduran Institute of Social Security

DOI:

https://doi.org/10.5377/pediatrica.v12i2.17602

Keywords:

Carvedilol, Beta Blockers, Bradycardia, Toxicity

Abstract

Beta-blocker intoxication is a rare clinical situation, closely related to major depressive disorders, with a higher prevalence in women. Severe episodes related to beta-blocker toxicity are classified as moderate to severe episodes. In the case of carvedilol with a toxic threshold of 50mg. Clinical Case: 16-year-old patient with a history of ingesting carvedilol at toxic levels and the only history of major depression. Discussion: Beta-blockers antagonize beta-adrenergic receptors, symptoms related to bradycardia and hypotension are common and can cause central nervous system involvement. Emergency treatment if the patient is captured in the first hour consists of performing a gastric lavage and applying activated charcoal. The use of crystalloids and the use of epinephrine or norepinephrine are proposed as first line management and in case of sustained bradycardia the use of atropine should be considered. Asymptomatic patients should be monitored for six hours.

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Abstract
79

Published

2024-02-26

How to Cite

Medina Pérez, E. A., Portillo, M., Banegas, L., & Velásquez, B. (2024). Beta Blockers Intoxication. Acta Pediátrica Hondureña, 12(2). https://doi.org/10.5377/pediatrica.v12i2.17602