Clinical and neurophysiological characterization of Guillain-Barré in the Teaching Hospital

Authors

  • Carmen J Aguilar Facultad de Ciencias Medicas, Postgrado de Neurología, Hospital Escuela
  • Marco T Medina Facultad de Ciencias Medicas, Postgrado de Neurología, Hospital Escuela
  • Rebeca Hernández Servicio de Cuidados Intensivos Pediátricos y Emergencia, Hospital Escuela
  • Claudia Amador Servicio de Cuidados Intensivos Pediátricos y Emergencia, Hospital Escuela
  • Martha Matamoros Servicio de Cuidados Intensivos Pediátricos y Emergencia, Hospital Escuela
  • José A Lara Pinto Epidemiólogo

DOI:

https://doi.org/10.5377/rct.v0i5.520

Keywords:

Guillain-Barré Syndrome, demyelinating, axonal, electrophysiological, electromyography, palsy

Abstract

Background and Objective. In Honduras, between 1989 and 1999, a study aiming to calculate the incidence of Guillain-Barré syndrome and flaccid paralysis in a pediatric population was developed in the Materno-Infantil Hospital. High compared to other studies, the ratio found at the time was 1.37/100.000 cases of Guillain-Barré syndrome per year and 1.89/100.000 cases of flaccid paralysis per year. The objective of this study was to determine the clinical and neurophysiological subtypes found in patients with Guillain-Barré syndrome in a Honduran pediatric and adult population, compared to a healthy control group.

Materials and Methods A transversal analytical study with consecutive patients following the criteria from Asbury at el was developed. The 29 patients, who were between the ages of 2 and 55 years, attended the Hospital Escuela and Materno Infantil during February 1, 2007, through August 2008. A clinical and neurophysiological evaluation was performed to the patients and the 58 healthy individuals. Motor function was assessed to the median, ulnar, peroneal, and tibial nerves, as well as the late F-wave response and the H reflex. The sensitive function of the median, ulnar, and sural nerves was evaluated following the technique described by Parano E, Uncini A. et al (9).

Results The demyelinating forms presented in 19 patients (65%); the axonal forms in 10 (35%). The former had greater severity and generated more incapacity, 9 of them requiring attention in the Intensive Care Unit resulting in more bed days, compared to the demyelinating forms (p=0,003).

Conclusions Similar to studies held at Northern China and Japan, a high incidence of the axonal forms of Guillain-Barré syndrome was found, presenting a greater severity and more bed days compared to the demyelinating forms.

Key Words: Guillain-Barré Syndrome; demyelinating; axonal; electrophysiological; electromyography; palsy.

DOI: http://dx.doi.org/10.5377/rct.v0i5.520

Revista Ciencia y Tecnología, No. 5, Segunda época, Diciembre 2009: 66-86

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How to Cite

Aguilar, C. J., Medina, M. T., Hernández, R., Amador, C., Matamoros, M. and Pinto, J. A. L. (2011) “Clinical and neurophysiological characterization of Guillain-Barré in the Teaching Hospital”, Jornual of Science and Technology, (5), pp. 66–86. doi: 10.5377/rct.v0i5.520.

Issue

Numero 5, Segunda Época, Diciembre 2009

Section

Diversity Theme

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