COVID-19 non-respiratory symptoms

Abstract

The usual symptoms of COVID-19 include fever, sore throat, dry cough, fatigue, muscle aches, anosmia, and hypogeusia. If pneumonia occurs, patients usually develop dyspnea. The atypical symptomatology of the disease, which is plenty, has not been widely narrated. This includes symptoms of the nervous system, such as agitation, confusion and even seizures, the eye, with conjunctivitis and epiphora, and the auditory system, with sensorineural hearing loss. The skin is also compromised, with findinds such as erythema with vesicles or pustules (erythema pernio-like or pseudo-chilblains), other vesicular eruptions, urticarial lesions, maculopapular eruptions and livedo or necrosis; the cardiac system, with acute myocardial damage and arrhythmias, and the gastrointestinal tract, with nausea, vomiting, and diarrhea. The epidemiological fact, that 50 % of individuals with diarrhea excrete the virus in their feces, is of public health concern. Other corporal areas involved are the renal system, 3 to 44 % of individuals with severe COVID-19 pneumonia present acute kidney damage; the hematological system, which presents a state of hypercoagulability that puts patients with COVID-19 pneumonia at risk of thrombosis, and finally, the multisystemic inflammatory syndrome in children.