Hidden renal disease in patients with sickle cell trait

Abstract

Sickle cell trait is usually seen as a benign condition but has been shown to cause different pathological consequences. Within these associations, one of the most important is the increased risk of chronic kidney disease in these individuals. This study aims to determine the prevalence of occult renal disease identified in people with the condition. The study was conducted in the population of the community of Ciriboya, Colón, Honduras in January 2015. With a sample of 20 people, over 18 years, which were identified with sickle cell trait in a previous research. Validated screening tool for Occult Renal Disease (SCORED) was applied in each participant, hemoglobin levels, glucose, blood pressure and proteinuria were determined, also medical history and risk factors were recorded. Data were entered and processed in the software Epi info 7. The sample included 13 women (65%) and 7 men (35%) in the age range between 19 and 83 years with an SD of 18.4, in which the prevalence of increased risk for kidney disease was found in 45 % of the study subjects. To give a special attention to people with sickle cell trait, since it is no longer considered a harmless condition, under the circumstances of the increase in pathological complications it can cause. Tracking those identified with an increased risk of kidney disease is recommended.