Hemolytic disease of the newborn by anti-erythrocyte antibodies maternal
DOI:
https://doi.org/10.5377/rct.v0i12.1706Keywords:
Newborn haemolytic disease, hemolysis, incompatibiltyAbstract
Hemolityc disease of the newborn is an immune complication of pregnancy; it is based in blood group incompatibility between mother and child. Most of the antigens involved in the process are part of the ABO system and, the D antigen of the Rh system, in other occasions it is caused by different blood systems antigens, such as Kell, Kidd, Duffy, Diego, Lutheran and MNS, among others. The mother can be immunized by previous blood transfusions with antigens not present in her blood, pregnancy, and miscarriages with maternal/fetal hemorrhage.
In order to investigate hemolityc disease of the newborn, the physician and the Immunohematology laboratory must perform a prenatal evaluation that includes obstetrical aspects, hemo-therapy and laboratory studies to help with the diagnosis, prognosis and best decision making for preventative measures. It is necessary the implementation of measures for prevention, maternal immunization to prevent hemolytic disease of the newborn.
DOI: http://dx.doi.org/10.5377/rct.v0i12.1706
Revista Ciencia y Tecnología, No. 12, junio 2013: 106-116
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